Cardiac Resynchronization Therapy (CRT)
PV Loops are used for real-time clinical decision making for pacemaker optimization related to tailoring vector settings, AV delay, and/or lead placement to each patient.
Heart Failure with Preserved Ejection Fraction (HFpEF)
PV loops are considered the “gold standard” for HFpEF diagnosis by monitoring several diastolic hemodynamic variables including, but not limited to: End-diastolic Pressure-Volume Relationship (EDPVR), Tau, and dP/dt.
Mechanical Circulatory Support
By using PV loops as a feedback mechanism, one can optimize a patient’s hemodynamic state resulting from acute or long-term mechanical circulatory support. Quantitative measures of ventricular energetics, diastolic function, and intra-ventricular dyssynchrony provide a comprehensive assessment of hemodynamic function tailored specifically to that patient.
Structural Heart Interventions
PV loops can be used as a real-time feedback tool regarding the efficacy of any structural heart intervention. To date, most users have focused on improving the efficacy of valve deployment in TAVR/TAVI and TMVR interventions or valve improvement via mitral valve clipping or valvuloplasty procedures.